Ionic strength (I) quantifies the total concentration of ions and the intensity of the electric field in a solution. It is the key to understanding how 'shielded' charges are in an electrolyte. High ionic strength can lead to 'salting out' of proteins, reduced solubility of salts, and changes in the speed of chemical reactions. The most important feature is the squared charge term (z²), which means a single Mg²⁺ ion contributes 4 times as much as a Na⁺ ion at the same concentration.