Diagnostic criteria for Disseminated Intravascular Coagulation.
Hemostasis Labs
DIC Diagnosis
ISTH Total0/ 8
ClassificationNegative for overt DIC
The score does not support a diagnosis of overt DIC. Repeat if clinical status changes.
Coagulopathy Assessment
ISTH Thresholds
≥ 5Suggestive of overt DIC
< 5Negative for overt DIC
About this calculator
Overview
Disseminated Intravascular Coagulation (DIC) is a serious disorder in which the proteins that control blood clotting become overactive. The ISTH (International Society on Thrombosis and Haemostasis) scoring system provides a validated algorithm for identifying 'overt' DIC in patients with an underlying condition known to be associated with DIC.
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Pro Tips
Only use this score if an underlying condition associated with DIC is present.
D-Dimer and FDP (Fibrin Degradation Products) are common markers used for the fibrin marker component.
Management focuses on treating the underlying cause, not just the laboratory abnormalities.
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Fun Facts
"DIC is always secondary to an underlying disease like sepsis, trauma, or malignancy."
"It involves simultaneous widespread clotting and excessive bleeding due to factor consumption."
"A score of ≥ 5 is highly sensitive and specific for the diagnosis of overt DIC."
"The scoring system should be repeated daily to monitor clinical progression."
