Laboratory Risk Indicator for Necrotizing Fasciitis.
Laboratory Markers
Probability Assessment
LRINEC Score0/ 13
Risk LevelLow Risk< 50%
Lower suspicion, but continue clinical vigilance.
Clinical judgment always supersedes the score. Crepitus, blistering, or gas on imaging require immediate surgery regardless of LRINEC value.
About this calculator
Overview
Necrotizing Fasciitis is a rapidly progressive and life-threatening soft tissue infection that requires immediate surgical intervention. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score was developed to distinguish necrotizing fasciitis from other soft tissue infections like cellulitis based on laboratory values.
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Pro Tips
If you suspect necrotizing fasciitis, do not wait for the lab results; consult surgery immediately.
Clinical signs like 'pain out of proportion to exam' or 'crepitus' are critical.
Repeat labs frequently, as the score can increase rapidly as the infection progresses.
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Fun Facts
"A score of ≥ 6 has a positive predictive value of about 92%."
"CRP is the most heavily weighted component; a CRP < 150 mg/L makes necrotizing fasciitis less likely."
"Hyponatremia (Sodium < 135) is a strong indicator of systemic toxicity in soft tissue infections."
"While helpful, the LRINEC score cannot definitively rule out the disease if clinical suspicion is high."
Formula: Based on values for CRP, WBC, Hemoglobin, Sodium, Creatinine, and Glucose.
